Targeted Metabolomics

Semi-targeted数据挖掘在MetaboScape^®is typically followed by targeted validation studies. A lower number of candidate target compounds is analysed in a larger number of samples often aiming for absolute quantitation. Together with Bruker Compass TASQ^®software, both targeted validation and untargeted metabolomics experiments are supported.

TASQ^®(Target Analysis for Screening and Quantitation) software is specifically designed to exploit high resolution, accurate-mass data generated by Bruker QTOF mass spectrometers. TASQ^®provides a turnkey solution to screen, confirm and/or quantify hundreds of compounds in a single analysis.

TASQ^®supports automatic generation of target compound lists based on implemented local query functions based on the SMPDB: The Small Molecule Pathway Database (http://www.ncbi.nlm.nih.gov/pubmed/19948758).

• Query target compound in SMPDB pathway database
• Retrieve list of target compounds from one or multiple pathway maps
  
• Targeted data mining for expected targets