Introduction to TopSpin for Solid-State NMR

Info:

Formerly AVANCE I - Solids

This 4-day course is designed to introduce users to TopSpin, provide a greater understanding of the many features within the software and practical experience at the spectrometer setting up basic solids experiments.

The course covers general probe and experiment setup for spin ½ nuclei, acquisition parameters, processing methods and plotting options. Topspin software installation, user administration and data management are discussed. Additionally, necessary basic system maintenance such as probe setup with magic angle adjustment and pulse length determination as well as cryogen fills are covered.

The lecture portion of the course is done in conjunction with the liquidsIntroduction to TopSpinand covers both TopSpin 3 and 4. Lectures are followed by laboratory sessions at the spectrometer for hands on experience.

Experiments:

• Sample preparation and rotor packing methods
• Setting up a CPMAS probe:
  - Setting of the magic angle
  - Pulse calibration
  - Probe shimmingg
  - Optimizing Hartmann-Hahn match condition

• Setup standard 1D¹³C CPMAS experiments and various spectral editing sequences
  

  - Spinning sideband suppression (TOSS)
  - Dipolar dephasing with and without TOSS,
  - CPPI – for signal assignment

• Setup and run pseudo 2D experiments
  

  - T1 relaxation experiments
  - For X and¹H nuclei.

• Setup CPMAS for different nuclei
  

  -¹⁵N,²⁹Si, or³¹P

• 2-Dimentional structure elucidation experiments
  

  - FSLG HECTOR

• Data processing and plotting

• Cryogen handling

Prerequisite:

An understanding of basic NMR concepts is strongly recommended for this course.

Date:

April 11 - 14 2022, Hybrid
2022年10月3 - 6 BillericaMA

Location:

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