原子力显微镜

纳米气管高速AFM

Highest imaging speed with up to 50 frames per second
NanoRacer

Lo más destacado

Nanoracer®高速AFM

的南oRacer® High-Speed AFM marks a quantum leap in quantitative imaging capabilities. The real-time visualization of dynamic biological processes with nanometer resolution has never been easier. The NanoRacer opens a world of new and exciting possibilities for Life Science applications, enabling researchers to gain an in-depth understanding of complex biological systems and molecular mechanisms, in a way not possible until now.

Exceptional
50 fps and 5000 lines/sec
小型悬臂能力,用于最低力成像和最小样品损坏。高级力量映射的最高扫描速度。
自动化
简单而直观的用途。快速结果。
尖端工程,出色的性能和稳定性。全自动设置。最先进的数据分析。
前沿
原子缺陷分辨率
Real-time visualization of dynamic biological processes with nm resolution. Understanding complex biological systems and molecular dynamics.

características

特征

高速AFM中的新章节:实时以50帧和真实5000行的实时动力学

DNA origami nanostructures containing 5 biotin binding sites on mica, imaged in fluid with streptavidin presence in closed-loop at 50 frames and 5000 lines/sec. Click on the image to watch the video.
纳米尺寸为生命科学应用开辟了一个新的和令人兴奋的可能性,使研究人员能够以直到现在的方式深入了解复杂的生物系统和分子机制,以了解:
  • Single molecule binding behavior
  • 二维蛋白质组件中的动力学
  • Enzyme activity monitoring
  • 蛋白质结构的组装和拆卸过程
  • DNA origami assembly
  • 蛋白质/蛋白质相互作用
  • 运动蛋白和膜运输动力学
  • Virus and bacteria morphology and dynamics

"So many things are still hidden in biological molecules. To uncover their unexplored secrets, there is a true need to directly observe individual molecules during their functional activity. The NanoRacer is the fastest commercial, high-speed AFM available, enabling their direct observation in real-time. A lot of innovative ideas have been incorporated for easy operation and high performance, and it is my utmost wish that many researchers will use the NanoRacer to reach their goals and make exciting discoveries."

Professor Toshio Ando, Nano Life Science Institute (WPI-NanoLSI), Kanazawa University, Japan

Outstanding resolution, renowned stability, remarkable accuracy

Atomic resolution of calcite crystal step edge, imaged in fluid, 3D topography 15 × 9 nm² [1], zoom 4 × 4 nm² [2]

Imaging atomic defects and sub-molecular resolution are now routine. The NanoRacer has the lowest noise levels of any commercial AFM system available, thanks to high precision electronics and enhanced accuracy positioning sensors in each axis.

的南oRacer reflects the pioneering work of Bruker’s BioAFM team in combining technological advances with proven stability, sensitivity, and ease of use.

  • Small cantilevers and lowest forcesfor minimum sample damage
  • 红外激光光热激发选项, for clean cantilever drive, easy setup and minimized perturbance of delicate samples
  • Advanced algorithms用于扫描仪控制和反馈
  • 最小化的力漂移用于长期实验
  • 最高带宽数字电子, with lowest noise, for maximum performance
  • Cutting-edge, high-speed power amplifier用于完美的扫描仪驱动器
  • 在所有轴上进行闭环扫描噪声水平最小,精度最高
封闭环中的云母+PLO上的流体中成像的单个DNA分子。序列[4] + [5]以50帧/秒为单位成像。单击图像观看视频。

Discover a new user experience - a complete system designed for convenience

  • 简单的样品和探针加载
  • Transportable sample carrierfor convenient sample preparation on the bench
  • Probe exchange in a few minutes
  • 无需校准thanks to closed-loop scanner design
  • Easy navigationwith integrated camera for locating areas of interest on the sample
  • Fluid exchange via direct injection
  • Newly designed 3-port liquid cellfor photothermal excitation

的南oRacer marks a new chapter in high-speed AFM and relegates complicated, time-consuming procedures to the past. Developed with the user in mind, the resulting robust and reliable design, with a host of new features, make the NanoRacer easy to use, even for newcomers to AFM.

All components are designed for convenient handling, from sample preparation through to fully motorized and automatic optical alignment. The streamlined handling enables easy data collection and fast results. A short time-to-data is vital for achieving dynamic results on active single molecule samples.

  • Automated cantilever alignment
  • 优化的漂移补偿
  • 自动光热激光对准选件
  • Internal camera with autofocus
  • Automated calibration of cantilever spring constant
Seamless handling for preparation and imaging with the transportable sample scanner. Prepare the sample conveniently on the bench and load into the NanoRacer to image.
软件

直观的V7软件,可证明可靠的易用性和惊人的尖锐图像

The closed-loop scanning and convenient interface make it easy to set the location directly from an overview image. Move from place to place with a single click, selecting interesting features and landing wherever you choose, without needing to adjust scan settings.
DNA亚稳态气泡的形成和闭合,在闭环中成像,以每秒2000行,z范围1.5 nm。圆圈说明了气泡在DNA分子上的位置〜30 nm的长度。
  • New workflow-based software design,非常适合多用户环境和成像设施
  • User-programmable software用于高级实验
  • ExperimentPlanner™enables full control of all system parameters, such as scanning positions, experiment settings or external fluidics modules
  • State-of-the-art data analysis and processingwith video creation and intuitive data storage


要以最高速度和最低的力扫描脆弱和移动样本功能,需要一个高度智能的控制软件:

  • 动态PID,用于精确研究样品形态的关键组成部分
  • Rapid response time对于悬臂远程检测系统,可以通过最短的反馈循环,最快的电子设备和智能FPGA算法来确保最短时间
  • Drift correctionr的定位点和自动探测器ealignment
  • Cantilever excitationwith photothermal option or Bruker’s proven DirectDrive™
  • Highest scan speedwith advanced adaptive scanner algorithms

Key Features

  • 50帧的最高成像速度和真实的5000行/秒,具有出色的分辨率
  • Intuitive V7 software for proven ease-of-use
  • 新开发的高速头和扫描仪单元
  • Automated cantilever alignment
  • 强大的同心设计,以实现最大的稳定性
  • 针对中小型悬臂优化
  • 尖端电子设备
  • Bruker的独家Peakforce Tapping可选

Aplicaciones

Applications

高速成像数据库

Bruker的Bioafms允许生命科学和生物物理学研究人员在细胞力学和粘附,机械生物学,细胞细胞和细胞表面相互作用,细胞动力学和细胞形态中进一步研究。我们收集了一个图像的画廊,展示了其中一些应用程序。

Especificaciones

Specifications

Operating Modes

Standard Operating Modes

Imaging modes

  • Tapping Mode™ with PhaseImaging™
  • Contact mode with lateral force microscopy (LFM)

Force measurements

  • Static and dynamic spectroscopy
  • 高级力量映射

可选模式

  • PeakForce™攻丝成像
  • Advanced AC modes such as FM and PM with Q-control & Active Gain Control
  • Higher harmonics imaging
  • 纳米流动
  • 实验计划™用于设计特定测量工作流程
  • RampDesigner™ for custom designed clamp and ramp experiments
  • 实验Control™功能用于远程实验控制

Accesorios

Accessories

市场上最宽的配件范围

Optical systems/accessories, electrochemistry solutions, electrical sample characterization, environmental control options, software modules, temperature control, acoustic and vibration isolation solutions and more. Bruker provides you with the right accessories to control your sample conditions and to perform successful experiments.

软件

Key Features

  • 50帧的最高成像速度和真实的5000行/秒,具有出色的分辨率
  • Intuitive V7 software for proven ease-of-use
  • 新开发的高速头和扫描仪单元
  • Automated cantilever alignment
  • 强大的同心设计,以实现最大的稳定性
  • 针对中小型悬臂优化
  • 尖端电子设备
  • Bruker的独家Peakforce Tapping可选

Webinars

Webinars

观看最近的生物防护网络研讨会

Our webinars cover best practices, introduce new products, provide quick solutions to tricky questions, and offer ideas for new applications, modes, or techniques.

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