The Vutara VXL comprehensive biological workstation for nanoscale biological imaging opens an affordable and easy-to-use path for both core facilities and individual investigators to enter the world of super-resolution imaging by incorporating Bruker’s industry-leading single-molecule localization microscopy (SMLM) technology in a streamlined system with compact footprint. The new system enables research on DNA, RNA and proteins, from macromolecular complexes and super-structures, to chromatin structure and chromosomal substructures, to studying functional relationships in genomes and in various subcellular organelles. This novel system also supports advanced spatial biology research in extracellular matrix structures, extracellular vesicles (EV), virology, neuroscience, and live-cell imaging. When combined with Bruker’s unique microscope fluidics unit, Vutara VXL enables multiplexed imaging for targeted, sub-micrometer multiomics in genomics, transcriptomics, and proteomics research.
Proprietary biplane technology, combined with a spatial filter in the emission light path, allows you to acquire 3D data with every acquisition. For thicker specimens, the Vutara allows you to easily perform a Z series and automatically localizes and reconstructs the entire volume.
The Vutara VXL is capable of imaging far from the surface of the coverslip to accommodate a wide range of sample types. Thanks to the proprietary biplane technology, the Vutara VXL with the SRX software can perform single-molecule localization microscopy on more sample types than any other commercial single-molecule localization microscope available. Making cultured cells, cell colonies, tissue sections, and entire model organisms accessible for your single-molecule localization experiments.
Vutara的定量定位显微镜套件使您可以将本地化变成有意义的结果。Vutara的SRX WorkFlow驱动软件可指导用户进行超分辨率单分子定位实验的设置,校准,成像,处理和分析。SRX软件将实时本地化处理与强大的3D可视化和分析工具相结合,以使研究人员快速创建出版物质量视频,图像和测量。
超分辨率定位显微镜(SMLM) |
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广场显微镜 |
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Excitation lasers (nominal laser power at diode) |
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平坦的照明 |
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Multi-color acquisition |
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Multi-plane imaging |
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相机 |
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客观的 |
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视野(FOV) |
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3D SMLM方法 |
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SMLM分辨率 |
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成像深度 |
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xy-stage |
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z-focus |
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漂移校正 |
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环境控制 |
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微流体单元用于定位显微镜应用中的顺序标记 |
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紧凑型桌面设计 |
34 cm x 40 cm x 34 cm, (1.2 ft x 1.3 ft x 1.2 ft) 35 kg (78 lbs)
33厘米x 53厘米x 32厘米(1.0 ft x 1.7 ft x 1.0 ft) 30公斤(65磅)
53 cm x 35 cm x 14 cm (1.7 ft x 1.1 ft x 0.4 ft) 8公斤(17磅) |
在典型的实验室环境中运行 |
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Vibration insulation included |
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Workflow oriented software for easy data acquisition |
STORM / dSTORM 棕榈 PAINT 其他基于眨眼的方式
Chromatin tracing Smfish(在开发中)
跟踪探针周期和位置 支持无限数量的探针
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SMLM处理 |
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粒子跟踪 |
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Fluidics Manager |
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Chromatin tracing (optional) |
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漂移校正 |
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统计分析工具 |
里普利的K功能 Pair correlation 最近的邻居
dbscan 光学 德劳尼 Particle counts Volume and density calculations 回旋和球形半径的确定 主成分分析(PCA) 质心的计算
Pearson’s correlation coefficient 曼德的重叠系数 强度相关商 交叉对相关 关节直方图 STORM-RLA
傅立叶环相关 标签密度分辨率分析 本地分辨率相关映射 最近的邻居分析 |
融合的visualization |
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Open data formats |
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网络附加存储(NAS)单元(可选) |
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借助SRX软件及其定量定位显微镜分析套件,Vutara VXL可以从生物样品中提供视觉和定量信息。通过定位单个分子,Vutara可以生成惊人的3D图像,同时提供深入的定量分析工具。
在设计学术界和行业的显微镜方面有超过15年的经验,我很自豪地为Vutara超分辨率显微镜的发展做出贡献。通过Biplane 3D检测和快速SCMOS成像,Vutara具有市场上最先进的超分辨率显微镜。
在扫描了市场上的超分辨率显微镜以及使用我们自己的样品进行个人访问和测试的大多数市售系统之后,我可以说我对Vutara的SR-350印象深刻。特别是,他们的成像软件的用户友好性以及超分辨率模式下的3D功能给我留下了深刻的印象。
Vutara has an excellent support team and staff as a whole making our transition to super-resolution a well-supported experience. If you're looking to advance your research by super resolution microscopy, I can confidently say that Vutara's systems are an excellent choice.
在比较电子显微镜时,特别是考虑样品制备时,您可以在超分辨率系统上获取的数据量令人难以置信。
Having published with a Vutara super-resolution system, I can confidently say that they offer one of the most advanced super-resolution microscopes available. Their attention to detail and ongoing close collaboration makes them one of my preferred microscopy vendors.