SkyScan 2214

纳米级的3D X射线显微镜

Ultimate Performance at your Command

herostageskyscan2214

Faits marquants

强调

300 x 400 mm
可以容纳的最大尺寸
Whether the sample is enormous or small, the SKYSCAN 2214 has the flexibility to image them all.
160 keV
穿透力
Quick change filament for switching between W for highest penetration or LaB₆ for highest resolution
<500 nm
true 3D spatial resolution
There are many ways to define resolution, but the most important is the ability to resolve 2 features in the resulting 3D model.

SKYSCAN 2214 – Nanoscale X-ray Microscopy

新的多尺度x ray nanotomograph SKYSCAN 2214 covers the widest range of object sizes and spatial resolutions in a single instrument. It opens unique possibilities for 3D imaging and exact modeling of all types of biological samples, including mineralized tissues, soft tissues, plants, insects, paleontological samples, etc.

The instrument allows scanning and 3D non-destructive reconstruction of the internal microstructure of objects as large as 300mm in diameter as well as submicron resolution for small samples.

The system contains an "open type" transmission X-ray source with <0.5 microns spot size and a diamond window. It can be equipped with up to four different X-ray detectors for maximum flexibility: flat-panel for large objects, 11Mp cooled CCD with wide field of view, 11Mp cooled CCD with medium field of view, and 8Mp cooled CCD for highest spatial resolution. Automatic variable acquisition geometry and phase-contrast enhancement allows best possible quality in relatively short scanning time.

The SKYSCAN 2214 is complemented by 3D.SUITE. This comprehensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization

Skyscan 2214步行视频

What is XRM? video

Caractéristiques

主要特征

SKYSCAN 2214 Features

Source

The SKYSCAN 2214 uses a latest generation open-type X-ray source. The source offers true spatial resolution below 500 nm, an X-ray energy up to 160 keV and source power up to 16 W. The source is practically maintenance-free with an extremely easy pre-aligned filament replacement procedure.

The SKYSCAN 2214 has an open-type (pumped) nanofocus X-ray source with diamond window. It produces an X-ray beam with peak energy from 20 kV to 160 keV and is supplied with two types of cathodes. The tungsten (W) cathodes operate in the full range of accelerating voltages up to 160 kV and provide a spot size down to 800 nm. The lanthanum hexaboride (LaB6) cathodes can be used for accelerating voltages from 20 kV to 100 kV and provide a spot size of the X-ray beam smaller than 500 nm to achieve the highest resolution in imaging and 3D reconstruction. The JIMA resolution pattern indicates that 500 nm structures can be easily resolved.

For long-term stability of the focal spot size and position of the emission point, the X-ray source is equipped with a liquid cooling system which contains a re-circulator providing precise temperature stability of the cooling fluid.

SKYSCAN 2214 Features

Detectors

Skyscan 2214最多可配备四台X射线摄像头,以实现最终的灵活性:三个具有不同分辨率和视野的CCD摄像机以及一个大面积平板检测器。可以单击单击所有摄像机。不同的CCD摄像机可以在系统一生中的任何时间重新安装。

All three CCDs can take images in the central beam position and in two offset positions to double the field of view. The images in the two offset positions are automatically stitched together with compensation of the shifts and possible intensity differences.

Using CCD detectors with small pixel size allows extension of high-resolution imaging and 3D reconstruction to large objects. The built-in detector flexibility enables adjusting the field of view and spatial resolution according to the object size and density. An advanced reconstruction from a volume of interest provides scanning of a selected part of a large object with high resolution without compromising image quality.

此外,可以通过使用偏置摄像头位置和垂直对象移动来水平和垂直增加视野。

SKYSCAN 2214 Features

In-situ stages

Skyscan 2214的高精度对象阶段支持直径300毫米的物体,重量为20公斤。空气旋转电动机可以以非常高的精度进行物体的精确旋转,并且集成的微位置阶段保证了完美的样品对齐。
Skyscan 2214具有一个较大且易于访问的样品室,可扫描大物体以及安装可选阶段。最大的空间可用于外围设备。

The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.

Bruker的加热和冷却阶段可以达到高达+80°C或低于环境温度30°C的温度。就像其他阶段一样,不需要额外的连接,并且对舞台有自动识别。使用加热和冷却阶段,可以在非镜头条件下检查样品,以评估温度对样品微观结构的影响。

The SKYSCAN 2214 is fully compatible with stages from DEBEN. With the included adapter, the DEBEN stage can be simply placed onto the rotation stage of the SKYSCAN 2214.

冷却阶段
物质测试阶段
Deben Stage

Applications

Highlighted Applications

Mineralized Tissues

The SKYSCAN 2214 provides ultimate nanoCT imaging performance without compromise. Four cameras are fitted – one large format 6 megapixel cMOS flat panel for imaging up to high voltages and large skeletal or dental samples, and a range of three small format detectors for the optimal choice of resolution and x-ray energy window for every conceivable bone sample scan.

亚微米体素扫描可提供骨骼骨细胞间隙和微尺度矿化结构的晶体清晰分辨率,以及纳米级分辨率下生物材料支架的结构。

Phase retrieval (Paganin) provides a new dimension of analysis of hitherto little studied bone micro-mineralization patterns.

使用绵羊,灵长类动物或类似模型的骨科研究通过14厘米扫描的视野和160kV X射线源处理。通过机械测试和温度控制阶段实现骨科和生物力学研究目标。

具有全面的3D和2D参数的形态计量学,其光密度测定法在临床前尺寸范围内包括BMD校准参考。高级3D图像分析功能包括3D注册,自适应阈值,Euler连接性,分形,各向异性和立体,过滤,布尔值逻辑运算符等。

Soft Tissues

具有亚微米像素大小的生物组织的体内纳米-CT扫描就像组织学或电子显微镜一样,但在真实的3D中,是一种不受破坏的内部结构的绝妙方法。对比剂或化学干燥可以通过进一步增强或区分组织密度来改善图像质量。Skyscan 2214在新成像学科的出现中发挥了领导作用 - 微型组织学和组织学学。

的无与伦比的已经rsatility of this system ensures that each sample will be scanned with optimized parameters and the best resolution and contrast.

Four cameras are fitted – a large format 6 megapixel flat panel for imaging up to high voltages and large tissue samples, and a range of three small format cameras for the optimal choice of resolution and x-ray energy window for every conceivable sample scan.

Comprehensive 3D image analysis capability including morphometry and densitometry, 3D registration, segmentation and advanced image processing methods.

动物生物学

MicroCT is exceptionally good for the visualization of the finest details of internal biological structures. This imaging method creates a nano-scale 3D x-ray attenuation map without harming or destroying the scanned object. Practically all biological tissues can be visualized and analyzed with little or no need of special sample treatment. Submicron voxel resolution allows imaging of small insect and plant or seed structures with powerful magnification and rich detail.

The space in the scanning chamber and the precision of the rotation stage make sure that all types of samples can be scanned, from the small zebrafish and preserved zoological and botanic samples to potted plants and rock-embedded fossils.

安装了四个摄像机 - 一个大格式6百万像素平板面板,用于成像高电压和大型样品,以及三个小格式摄像机的范围,用于针对每个可能的生物学样品扫描的最佳分辨率和X射线能量窗口的最佳选择。

The software suite enables morphometry with comprehensive 3D and 2D parameters, and advanced 3D image analysis functions include 3D registration, adaptive thresholding, Euler connectivity, fractal, anisotropy and stereology, filtering, Boolean logical operators and much more.

Spécifications

SKYSCAN 2214 Specifications

特征

Specification

Benefit

X-ray source

20-160 kV

16 W最大

用户可交换的灯丝

Optimize for max power (W) or max resolution (LaB6)

可旋转的钻石窗口最大寿命

X射线检测器

6 Mp active pixel flat-panel

11 Mp large format cooled CCD

11 MP中格式冷却CCD

8 Mp hi-res cooled CCD

Variety of pixel and detector sizes allow balance between detector resolution, coverage and counting statistics

Available with 1, 2, 3 or 4 detectors

现场升级添加探测器

Image Formats

Up to 8000 x 8000 x 2300 pixels after a single scan

用户可选的图像尺寸允许平衡数据集大小和所需分辨率

软件允许缩小数据收集后

Resolution

60 nm smallest pixel size
<500 nm低对比度分辨率(10%MTF)

简单的图形控制,用于优化基于选定检测器,样品和检测器距离的实验分辨率

可调节的源重点尺寸以平衡最大功率和分辨率

Positioning Accuracy

旋转<50 nm
带有气动水平的抗振动花岗岩平台

Air bearing sample stage provides smooth rotation

简单的Chuck风格安装样本帖子

Mechanical and electrical interface for advanced materials research stages

最大对象大小

300 mm in diameter (140 mm scanning size)

400 mm in length

最大的对象重20公斤

Both the power and room to scan large samples

Precise positioning of small samples near the source to maximize magnification

方面 W 1800 mm x D 950 mm x H 1680 mm

Weight: 1500 kg

有效设计以优化实验室空间的使用

Source maintenance access via interlocked large sliding door

Logiciels

POSITION, SCAN, RECONSTRUCT and ANALYZE

Bruker XRM solutions include all software needed to collect and analyze data. An intuitive graphical user interface with user guided parameter optimization support both expert and novice users. By using the latest GPU powered algorithms, reconstruction time is substantially reduced. CTVOX, CTAN and CTVOL combine to form a powerful suite of software for both qualitative and quantitative analysis of models.

测量软件:
Skyscan 1272 - 仪器控制,测量计划和收集

Reconstruction Software:
NRECON – Transforms the 2D projection images into 3D volumes

Analysis Software:
Dataviewer- 逐片检查3D卷和2D/3D图像注册

CTVOX– Realistic visualization by volume rendering

ctan- 2D/3D图像分析与处理

CTVOL– Visualization of surface models to export for CAD or 3D printing

Nouveautés et événements

Support

Skyscan 2214-服务betway手机客户端下载与支持

Available services include

  • 高技能故障排除专业人员的帮助办公桌支持,隔离和解决硬性和软件问题
  • Web-based remote instrument service for service diagnosis and applications support
  • Merged reality support with Help Lightning – a virtual engineer at your side (video
  • Planned maintenance, according to your requirement
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • 合规服务安装资质betway手机客户端下载, operational qualification / performance verification
  • Site planning and relocation

Bruker Support

On oursupport website你会找到:

Software Updates

  • System software updates are available online to registered users.

文档

  • Product manuals and installation guides are available online to registered users.

Labscape

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

实验室维护协议,现场点播和增强实验室旨在为现代实验室提供一种新的维护和服务方法betway手机客户端下载