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Bruker Introduces Four Next-Generation Preclinical Imaging Systems at WMIC 2015

September 03, 2015

New Breakthrough PET/CT and PET/MRI Systems Change Performance Paradigm

HONOLULU--(BUSINESS WIRE)-- Bruker(NASDAQ: BRKR) today introduced four important new preclinical imaging systems at the World Molecular Imaging Congress2015 (WMIC,www.wmis.org) in Honolulu, Hawaii. The novel products launched at WMIC each deliver improved performance and convenience for routine imaging, and open new horizons for advanced translational research, while Bruker’s platform philosophy facilitates multimodal imaging projects. Researchers will gain a more complete picture and deeper insights into the causes, progression, potential diagnosis and treatment of disease, accelerating the translation of preclinical results to clinical progress.

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Bruker's High-Sensitivity Xtreme II Optical Molecular Imaging System (Photo: Business Wire)

Bruker's High-Sensitivity Xtreme II Optical Molecular Imaging System (Photo: Business Wire)

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Next-Generation Albira™ Si PET/SPECT/CT System
一个革命性的和专有gridlessPET detector architecture, which is also available for Bruker’s new PET/MRI systems, makes theAlbira Sithe most advanced and highest performance preclinical PET system on the market. It delivers, for the first time, sub-millimeter spatial resolution across the full radial field of view (FOV), increasing the high-resolution FOV by an order of magnitude compared to traditional PET systems. This breakthrough capability, combined with exceptional count rate performance and outstanding PET sensitivity, makesAlbira Sithe preferred system for dynamic and gated PETin vivostudies.

TheAlbira Sioffers all benefits of integration with SPECT and CT. The micro-CT provides anatomical reference images and attenuation corrections for PET and SPECT imaging. In addition, theAlbira Siis compatible with Bruker’s Multimodal Animal Beds for cross-platform MRI and optical molecular imaging.

教授 Jose Benlloch, Director of the Institute for Instrumentationin Molecular Imaging (I3M) at the Polytechnical Universityof Valenciain Spain, explained: “The new Silicon PM detector technology has major advantages in providing better PET position, energy and timing resolution, and it is compatible with MRI. An additional significant benefit of our unique, continuous crystals technology pioneered at I3M, is the greatly enhanced DOI detection for highest resolution across the entire field of view, which is very beneficial for virtually all preclinical PET applications.”

New BioSpec®3T Preclinical MRI System with Superior Cryogen-free Magnet
The newBioSpec 3Tfeatures breakthrough cryogen-free magnet technology that overcomes the reliability limitations of older cryogen-free magnets that quench within minutes after power outages or cooling water failures. TheBioSpec 3Twill remain at field 25x-100x longer after a disruption. Cryo-cooler maintenance can conveniently be done at field by Bruker’s magnet service engineers.

TheBioSpec 3Tfeatures an 18 cm magnet bore, and is upgradable to PET/MRI. Adding Bruker’s proprietaryMRI CyroProbe™for mice and rats, MRI sensitivity and spatial resolution can optionally be increased to be comparable to conventional 7T MRI. The newParaVision 6software features validatedin vivoprotocols, and an easy-to-use preclinical user interface that unifies workflows across different modalities, with facile multi-modality image fusion.

Next-Generation PET/MRI System
Combining the breakthroughAlbira SiPET detector technology with superior MRI soft tissue contrast are now offered in the newBioSpec 3TPET/MRI, in one compact instrument. Built-in Multimodal Animal Beds are fully compatible with other Brukermolecular imaging systems. Other PET/MRI combinations may be available upon request.

New, High-Sensitivity Xtreme II Optical Molecular Imaging System
The integration of a new CCD camera brings a new level of sensitivity, speed and versatility. By deeper cooling of the camera and low noise electronics, new levels of performance during low-light applications, such as bioluminescence and Cerenkov imaging, can now be achieved.

Versatility is maintained with five imaging modalities provided as standard within theXtreme II, allowing for co-registration of molecular events with access to bioluminescence, multispectral VIS-NIR fluorescence, unique direct radioisotopic imaging, and Cerenkov radiation. A high speed digital X-ray scanner with industry-leading resolution and reflectance modes enhance the optical functional images with morphological features.

Dr. Wulf Jung, President of Bruker’s Preclinical Imaging Division, commented: “At WMIC 2015, Brukeris demonstrating clear performance leadership in preclinical PET/CT and PET/MRI, and we are pleased to respond to our customers’ demand for a translational research 3 Tesla preclinical MRI with robust cryogen-free magnet technology. Our optical molecular imaging capabilities have also been further enhanced to meet customer expectations.”

About Bruker Corporation(NASDAQ: BRKR)

For more than 50 years, Brukerhas enabled scientists to make breakthrough discoveries and develop new applications that improve the quality of human life. Bruker’s high-performance scientific research instruments and high-value analytical solutions enable scientists to explore life and materials at molecular, cellular and microscopic levels. In close cooperation with our customers, Brukeris enabling innovation, productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy, nano-analysis and industrial applications, as well as in cell biology, preclinical imaging, clinical research, microbiology and molecular diagnostics.

For more information, please visit:www.fatactor.com/preclinicalimaging

Source: Bruker Corporation

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