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Bruker Introduces the rapifleX™ MALDI-TOF/TOF at HUPO

September 28, 2015

新颖的10 kHz Rapiflex提供突破性的TOF/TOF/TOF性能和鲁棒性,可用于蛋白质组学,MALDI组织和生物制药应用中的主要结构和PTM测定

VANCOUVER, British Columbia--(BUSINESS WIRE)-- At the 14th 人类蛋白质组组织世界国会(hupo), Bruker今天宣布了新的Rapiflex马尔代-TOF/TOF mass spectrometer. MALDI-TOF/TOF is established as a powerful tandem mass spectrometry method for in-depth protein analysis. With its redesigned, next-generation TOF/TOF ion optics, theRapiflexsystem now offers significantly higher speed, mass resolution and mass accuracy.Rapiflexintegrates a novel, 10 kHzsmartbeam™ 3Dscanning laser design for breakthrough mass-spec imaging capabilities with dramatically improved spatial resolution, image contrast and quality, and a new ion source for superior robustness and throughput in pathology research.

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New rapifleX™ MALDI-TOF/TOF (Photo: Business Wire)

New rapifleX™ MALDI-TOF/TOF (Photo: Business Wire)

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Tissue- and cell-type specific proteomics is a major advance for relevant biomarker discovery and identification, and requires MALDI tissue imaging studies which include the identification of detected biomarker candidates for validation and the subsequent development of targeted assays. TheRapiflex马尔代-TOF/TOF extends the马尔代thistuetyper® imaging capabilities with rapid, spatially resolved MS/MS data. It supports the patentedImageIdMALDI成像队列研究中生物标志物发现的™工作流程通过在自下而上的成像研究中获得胰蛋白酶肽的匹配来进行研究。

Dr. Dietrich Hauffe, Executive Vice President for Life Science Mass Spectrometry at Bruker Daltonics, commented: “With theRapiflex马尔代-TOF/TOFintroduction, we can now offer both, greatly enhanced TOF/TOF performance for structural characterization, and breakthrough MS imaging capabilities for cutting-edge proteomics research laboratories, for biopharma customers, and for clinical researchers in pathology. Its unparalleled speed, throughput, structural capabilities, imaging capabilities, as well as MALDI ease of use and robustness, make the newRapiflex马尔代-TOF/TOF a game-changing new research and validation tool.”

有关Rapiflex马尔代-TOF/TOFsystem

除了下一代组织成像性能外,RapiflexMALDI-TOF/TOF系统非常适合生命科学研究和生物制药实验室中的详细蛋白质表征。这Rapiflex马尔代-TOF/TOF system will improve many protein characterization tasks:

  • Peptide mass fingerprints for protein identification
  • 快速识别翻译后修饰(PTM)
  • Fast identification of impurities
  • 自上而下的蛋白质测序
  • T3-Sequencing to identify or confirm suspected modifications or sequence alterations at protein N- or C-termini. T3- 为蛋白质末端结构确定申请了专利。
  • Fully automated Disulfide Bond analysis of intact proteins without a priori assumptions usingDisulfideDetect™方法和软件。

Rapiflex™马尔代-TOF/TOFsystemis for research use only.

关于 Bruker Corporation(NASDAQ: BRKR)

For more than 50 years, Bruker使科学家能够做出突破性的发现并开发新的应用,以改善人类生活的质量。布鲁克的高性能工具和高价值分析解决方案使科学家能够在分子,细胞和微观水平上探索生命和材料。必威手机客户端

与客户密切合作, Brukeris enabling innovation, productivity and customer success in life science molecular research, in applied and pharma applications, in microscopy, Nano-analysis and industrial applications, as well as in cell biology, preclinical imaging, clinical research, microbiology and molecular diagnostics. For more information, please visitwww.fatactor.com.

来源: Bruker Corporation

Investor Contact:

Bruker Corporation

Joshua Young, 1 978-667-9580, ext. 1479

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Media Contact:

Bruker Daltonics

鲍勃·加尔文(Bob Galvin),44 7881 811287

Vice President, Business Unit Omics & Biopharma

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