生物镜解决
Punti Salienti
生物镜解决
布鲁克’s BioScope Resolve BioAFM features the highest resolution atomic force microscopy imaging and most complete cell mechanics capabilities available for use with an inverted optical microscope. BioScope Resolve incorporates Bruker’s exclusive PeakForce Tapping technology to enable researchers to achieve the highest resolution biological imaging and piconewton-level force measurements and spectroscopy at every pixel. The system’s real-time synchronization of optical and atomic force microscopy data opens the door to previously inaccessible data, including physical structure, biochemical interactions, and mechanical properties, to provide unique insights into life sciences research.
Caratteristiche
准确，可重复和完整的单元力学数据
最终力量控制-PeakforceQNM®，已成为纳米力学映射的首选模式。使用新算法，它在活细胞上提供了PN力的最高分辨率性能图。加上“无触摸”尖端校准，PeakForce QNM可提供活细胞的最快定量机械表征，以从125 Hz至2 kHz的驱动速率为每个像素提供完整的力曲线。
最宽的坡道率-At the core of quantitative nanomechanical maps are force-distance curves. Beyond characterizing elastic response, ramp rate dependent data provides insight into viscoelasticity or into molecular interaction times at the single molecule level. With our newFASTForce Volumecovering rates from sub-Hz to 300 Hz, andPeakForce Tappingextending to 2 kHz, we provide the widest range of ramp rates for single points and imaging while maintaining pN force control.
覆盖整个频谱-Our new RampScript™ allows the user to build, control and record complex nanomechanical measurements for use in protein pulling, ligand-receptor interaction, cell relaxation and viscoelastic probing. Its low force trigger capability, and latency-free implementation build on the system’s core performance to provide the most accurate script execution and force control. Ramping scripts are created in an intuitive drag and drop process and provide ultimate flexibility including per segment optical synchronization.
Cell Dynamics Without Compromise
Fast Tapping on living cells-Bioscope Resolve是唯一可以快速扫描的生物防护剂，同时提供了实时捕获活细胞动态行为所需的大型压电扫描仪范围（XYZ = 100µm x 100µm x 100µm x 15µm）。在与细胞过程有关的时间标准进行高分辨率AFM研究方面，快速攻击能力确实是向前迈出的一步。加上高级光学显微镜和环境控制的整合，实时细胞研究从未如此简单。
无缝组合荧光和生物力学
扩大的测量可能性- Miroview GUI通过完全同步的AFM图像，力图和具有光学图像和数据的单力曲线确保专家数据生成。
出色的光学整合- 由于考虑到研究人员的应用程序，Bioscope解决AFM与光学显微镜无缝合作。像素的像素像素，按线路和图像划分，光学同步提供了在AFM上从未见过的灵活性。
The perfect environment- 带有新的声学罩，工作站以及一套完整的生命科学研究配件，例如样品加热器，灌注电池和自上而下的摄像头，Bioscope Resolve可提供您所有的生物防护研究需求。
Applicazioni
生物镜解决Data Gallery
辅助
网络研讨会
最近的网络研讨会
证词
听听我们的客户要说的话
以前无法解决Microvilli这样的活细胞的最优质结构，但是现在，随着Bioscope解决峰值攻击的改善，我可以在一小时内轻松地对其进行成像。
For the first time, bio-AFM analysis can directly correlate high-resolution molecular structures with function, on the same cell. BioScope Resolve provides the dynamic range and resolution necessary to allow a deeper understanding of structure-function relationships at the cell and tissue surface.
借助AFM上的Peakforce QNM和多功能操作模式的独特功能，我们准备扩大对具有超高分辨率的生物样品的微型和纳米型操纵研究。
