ForcerObot®300
ハイライト
ForcerObot®300
Using the ForceRobot® overcomes the limitations of traditional force measurements. The ForceRobot® automates routine procedures and provides software support for experimental design, data acquisition and evaluation.
特長
更快的时间
对力光谱实验的有意义解释的基础是大量可再现数据集。ForcerObot®通过使常规程序自动化并为实验设计，数据采集和评估提供智能软件来克服传统力量测量的局限性。在无人看管的模式下，在几个小时内生成了数万个力曲线，并且在处理前会自动滤除无事件的力曲线。必威官网体育下载
集成的CCD摄像机可确保轻松地对齐激光检测系统，还允许探测和样品观察以查找样品斑点或监视尖端或样品更改。最后，当系统在无人看管的操作中提供高质量的数据时，用户可以专注于实验结果。
更高的数据质量和数量
The quality of the force spectroscopy data is vital for successful analysis. The lowest electronic noise floor and the most rigid mechanical design are essential. The highest accuracy and stability of the instrument is ensured by integrated capacitive position sensors with exceptional performance. For minimized drift, the system design is symmetric.
For the detection of smallest variations in force curves JPK improved the sensitivity and increased the detection bandwidth without compromising the noise levels. The high sampling rate and virtually unlimited number of data points per force curve complete this unique instrument.
完美的环境控制
The mechanical properties of single molecules are strongly influenced by their environment. The unique environmental control of ForceRobot® is tailored to this requirement, with heating and cooling available over a wide range of temperatures. This enables the study of biological samples at physiologically relevant temperatures or polymer samples in phase transition. The JPK Fluidics Module™ allows the design and performance of experiments with different buffer composition, pH value or chemical agents. The ForceRobot® is fully compatible with a wide range of different JPK liquid cells and temperature stages.
Application examples:
- Protein (un)folding and receptor-ligand interactions
- Analysis of adhesion forces of single macromolecules for surface chemistry and polymer science
- DNA的弹性反应或熔化
- 单分子机械性能，例如肌肉蛋白，合成生物聚合物，碳水化合物或蜘蛛丝蛋白
- 小分子在蛋白质上的结合定位（例如，膜蛋白上的抑制剂）
- Quantification of kinetics, affinity and energy landscapes of biological interactions
- 胶体探针和纳米构造实验
Key Features
- 具有最高灵活性的全自动力光谱仪
- 使用JPK的Directoverlay™软件与单分子荧光结合使用尖端力光谱和力量映射
- Automated laser and detector alignment
- 自动悬臂漂移补偿
- Advanced and dedicated software with ExperimentPlanner™, RampDesigner™ and built-in data batch processing
- 分子识别映射
- Fits to the Vortis™ controller
アプリケーション
ForcerObot®300Data Gallery
布鲁克’s BioAFMs allow life science and biophysics researchers to further their investigations in the fields of cell mechanics and adhesion, mechanobiology, cell-cell and cell-surface interactions, cell dynamics, and cell morphology. We have collected a gallery of images demonstrating a few of these applications.
仕様
Specifications
- 200,000 curves per 24 hours in unattended mode while varying parameters such as temperature or loading rate
- Highest data density with virtually unlimited points per force curve
- 可以在倒置光学显微镜或独立版本上操作
- 即使有功能化技巧，智能和自动化的方法即使
- 用户友好的自动激光器和检测器对准消除了长期测量的悬臂漂移
- 具有高精度样品阶段的自动样品定位或映射
- Full remote instrument operation through internet
アクセサリー
市场上最宽的配件范围
光学系统/配件，电化学解决方案，电气样品表征，环境控制选项，软件模块，温度控制，声学和振动隔离溶液等等。Bruker为您提供正确的配件，以控制样本条件并执行成功的实验。
ウェビナー
观看最近的生物防护网络研讨会
我们的网络研讨会涵盖了最佳实践，介绍新产品，为棘手的问题提供快速解决方案，并为新应用程序，模式或技术提供想法。