Industries Overview

Life sciences is transforming and the drug discovery paradigm is changing. Many discovery programs are now conducted by external research partners. This rapid change in Pharma’s business model presents enormous data challenges in sharing and security. Secure and flexible data management systems enable collaboration, sharing and innovation across all aspects of the partner network.

今天的大多数研究实验室大规模quantitie过程s of incoming data from collaborative research and, most often, from CRO partners. The geographically separated CRO facilities make hard copy data entry almost useless. If an electronic notebook application is already deployed, it can be difficult, time-consuming and error-prone to review and manually enter external data that is supplied from an alternative lab notebook application.

一个主要的用例Arxspan笔记本是securely gather data from CROs and seamlessly approve and upload that data into electronic notebooks existing at Pharma. Arxspan provides standard integration to enable this type of workflow.

研究经理可以查看、搜索和批准阴极射线示波器experimental data prior to incorporating it into their existing notebook. Optionally, if desired for security, data delivered by Arxspan can be deleted once the data transfer is complete.

This approach offers valuable benefits, including the following list.

安全

CRO users have no visibility into Pharma’s IT infrastructure. This security arises by use of the Arxspan system as the CRO notebook system and not by configuration or permission changes in existing corporate notebook systems that would jeopardize internal security.

Visibility

Monitor CRO research and collect output electronically, including electronic signatures and witnessing, if desired.

Efficiency

CRO data are electronically pushed to the internal electronic notebook platform, eliminating the time and process of manually entering relevant data.

Compliance

Arxspan Notebook is 21 CFR Part 11 compliant and offers optional SAFE-BioPharma support.

加油创新生产力是研发成功的关键。在这个协作时代，密集的环境和有效的数据管理至关重要。

Arxspan’s cloud-based Arxspan ELN, Arxspan Registration, Arxspan Inventory and Arxspan Assay system is a research-centric knowledge management platform that can help an organization realize the value of its data during this age of information explosion by ensuring quality, consistency and secure access. Its straight-forward turn-key web-browser solution eliminates IT pain for start-up Biotechs have suffered in the past.

查找此处列出的ARXSPAN实验室软件解决方案的一些好处。

安全

An organization’s most valuable asset is the IP from its research, be it internal or out-sourced. Data standards, security and compliance with 21 CFR Part 11 are included in the software.

Data Integrity

Low cost data migration from legacy systems is performed by the Arxspan team of professionals.

Visibility

安全的统一数据存储消除了由锁定在不同数据源中的数据引起的问题，包括个人驱动器，纸质实验室笔记本电脑，网络和数据仓库。现在，组织可以通过即时可搜索的访问，分析和对IP的洞察力来实现在研究生命周期中获得的累积利益。

Compliance

ARXSPAN ELN为21 CFR第11部分符合条件，并提供可选的安全双重支持。

Efficiency

ARXSPAN易于使用的界面以科学家的工作方式工作，并减少了耗时的手动流程以及流线工作流程和信息交换。

Cost

Cloud-based deployment lowers the set up costs to organizations as well as reduces IT support and maintenance costs.

Flexibility

Deployment of the Arxspan software is flexible with cloud-based or on-premise options. The web based user environment is accessible from any device or operating system. Arxspan’s Notebook, Registration, and Inventory can be purchased as a suite or as stand alone modules.

Avoids Data Silos

消除组织中的数据孤岛和手动流程，并寻求更快，更具成本效益的资本化研发支出的方式。

该业务是否是新颖的有机金属催化剂，组合化学库，手性生物分子的手性构建块，用于塑料行业的单体，石油添加剂或其他多种化学物质，新分子只有在能够注册，搜索，搜索和指导和指导的情况下才有用走向新用途。

一个以分子为中心的平台准确，安全地解释结构对于组织开发其化合物的全部价值至关重要。从板凳上衣到试验工厂的科学家，从一个实验室中的新分子到整个组织的开发都需要易于实验和数据输入，以及实验性可搜索性和可伸缩性，以跟踪千篇一元到千克数量。ARXSPAN电子笔记本，注册和库存系统从方便的网络接口无缝地工作。

Visibility

安全的统一数据存储消除了由锁定在不同数据源中的数据引起的问题，包括个人驱动器，纸质实验室笔记本电脑，网络和数据仓库。现在，组织可以通过即时可搜索的访问，分析和对IP的洞察力来实现在研究生命周期中获得的累积利益。

Full Chemical Structure

An organization’s most valuable asset is the IP from its research, be it internal or out-sourced. Data standards, security and compliance with 21 CFR Part 11 are included in the software.

Flexibility

Low cost data migration from legacy systems is performed by the Arxspan team of professionals.

带上自己的结构绘图工具

Deployment of the Arxspan software is flexible with cloud-based or on-premise options. The web based user environment is accessible from any device or operating system. Arxspan’s Notebook, Registration, and Inventory can be purchased as a suite or as stand alone modules.

Efficiency

ARXSPAN易于使用的界面以科学家的工作方式工作，并减少了耗时的手动流程以及流线工作流程和信息交换。

The Arxspan Notebook platform allows companies to manage all incoming contract research organization (CRO) work in real time: placing experimental result data into experiments, registering small molecule or biological compounds, registering assay data, or placing materials into inventory locations.

Arxspan accommodates view only, write-only, or view-write CRO access to any client information in the system, with clients variably controlling information sharing capability among scientists within a CRO as well as across CRO organizations. CROs can sign off on work completed and internal managers can review and witness this work, as well as generate custom reports of some or all of the relevant data. Should a project or relationship end, CRO scientists can be instantly removed from either the relevant project or the Arxspan system completely, with legacy experimental data remaining intact and accessible by the client.

While ramping up relationships with CROs, scientific companies find that they are struggling with having informatics architecture and process that allow for optimal management of incoming CRO data.

研究数据管理和交换是瓶颈s, data quickly becomes decentralized and unsearchable, and integration with in house systems for bulk import of information is cumbersome. Receiving CRO data quickly and with higher quality and efficiency, as well as being able to effectively search and share it, are important factors in the CRO/Client partnership.

Arxspan’s cloud-based suite of applications can facilitate data transfer and collaboration between organizations, allowing for efficient sharing of results and reducing bottlenecks of knowledge transfer. Arxspan’s straight-forward, turn-key web-browser informatics solutions eliminate the IT pain of managing external CRO data.

安全

An organization’s most valuable asset is the IP from its research, be it internal or out-sourced. Data standards, security and compliance with 21 CFR Part 11 are included in the software.

Compliance

ARXSPAN易于使用的界面以科学家的工作方式工作，并减少了耗时的手动流程以及流线工作流程和信息交换。

Visibility

Low cost data migration from legacy systems is performed by the Arxspan team of professionals.

Efficiency

Deployment of the Arxspan software is flexible with cloud-based or on-premise options. The web based user environment is accessible from any device or operating system. Arxspan’s Notebook, Registration, and Inventory can be purchased as a suite or as stand alone modules.

Advantageous

Demonstrate a clear and competitive advantage while moving to a paperless internal environment with the Arxspan Notebook suite.

The petrochemical industry produces petrochemical, chemical, and petroleum materials to make products as diverse as fuel, solvents, detergents, adhesives, polymers, oligomers, resins, fibers, elastomers, lubricants, and gels.

全球石化提供商面临与其运营相关的许多当前挑战，包括满足需求不断增长，管理成本，遵守环境/健康/安全法规，实现生产力和技术的提高，将全球研究和技术运营联系起来，与合作伙伴组织合作以及利用运营的运营合并和获取活动的协同作用。通过提高研发生产率和生产效率，正在应对这些挑战中的许多挑战。

To accomplish these goals, scientists working to research, produce, and refine existing and new molecules require a sharable and searchable repository for entering reaction data, registering new chemicals or assays, and managing inventory from bench top research to large scale production processes.

The Arxspan Notebook platform provides an intuitive and scalable electronic laboratory notebook for conducting chemical research and sharing results across a globally distributed scientific workforce — from laboratory to pilot plant to refinery.

The Arxspan Platform is cloud-based, allowing for scientists around the globe to share their scientific and technical data securely and in real time. External partners at collaborating companies or CROs can be added or subtracted from the system with a click of a button. Chemistry, organic chemistry, and polymer chemistry structures are recognized for synthesis, registration, inventory, tracking, and IP searchability through ChemDraw®, Accelrys Draw®, JChem®, or Marvin®. Arxspan’s easy to use interface works the way scientists work; it reduces the time consuming manual processes and streamlines workflow and information exchange. Duplicate recognition in the system eliminates costly repetition of chemistry. Experiments within Arxspan allow scientists to manage, search, and share information globally, and decision support tools allow for advanced sorting and analysis of all research data.

Speed scientific innovation and productivity in your organization and allow for faster product development timelines.

Manufacturing functions across all industries continually face pressure to streamline operations, reduce costs, and adequately meet all technical, legal, and regulatory requirements.

In order to accomplish these goals, manufacturers must ensure tight control over all sequences of tasks in the laboratory. Data storage and retrieval must be simplified, and information must be easily shareable across multiple functions and locations within an organization. Experiments and processes must have adequate audit trails and traceability to ensure intellectual property protection and adherence to regulatory requirements associated with manufacturing and related processes. Furthermore, monitoring of personnel workflows and review capability of experiments is important.

Requiring data entry into electronic laboratory notebooks from the very beginning of all processes ensures that all of these requirements can be met. ELNs document work product in a central format, create secure and real-time data access, allow for collaboration, ensure full audit trail of all processes, and allow for management to conveniently review work product.

Arxspan Notebook handles the strictest manufacturing requirements by offering an ELN that securely manages all research and process data while at the same time being flexible enough to adapt to new or changed processes. The system provides different types of experiments to manage chemical, biological, or engineering-related manufacturing as well as analytical characterization of manufactured compounds or components. Templates for repetitive procedures can be setup, facilitating process automation and elimination of manual errors. For chemical and biological manufacturing, Arxspan offers useful functionalities such as reaction tracking, automated compound checking for regulatory compliance, and an affiliated database for tracking manufacturing-related degradants and impurities.

The cloud-based aspect of Arxspan Notebook ensures effective, duplication-free collaboration across all internal technical groups as well as external groups such as CROs. Experimental notebooks can be shared with complete or restricted access to any group or individual, protocols can be copied from one operator to another, and process/quality test requests can be established.

All experimental protocols can be signed by operators and approved or rejected by managers overseeing operations. Arxspan Notebook features the SAFE BioPharma signature service for identity authentication associated with digital signatures in the pharmaceutical industry. Arxspan is GLP certified and 21 CFR Part 11 qualified.

The optional Arxspan Inventory module integrates with Arxspan Notebook and allows users to decrement inventory for use in procedures or experiments. Users can keep separate inventory stock for research, process development, manufacturing, and quality operations. Attachments such as MSDS and hazard, safety, and flammability reports can be stored in the system.

The optional Arxspan Assay module enables registration of assays and procedures for manufacturing as well as for process and formulation development. Users can register manufacturing trial settings and results, develop and document intellectual property associated with processes, and search and sort data for decision making.

临床研究是一个不断扩展的研究领域，因为学术界，政府和行业寻求提高临床试验的成功率以及新药物，设备和诊断测试的总体功效。

在基准研究阶段，科学家需要标准的电子实验室笔记本功能来记录其化学和生物学实验。随着化合物的进展到动物测试阶段，记录用于处理动物和材料的工作流变得很重要。必威手机客户端在样本处理实验室中，分析师需要一个更具结构化的平台，以确保符合正确的以下程序，准确记录结果并准确跟踪样品。临床研究人员需要ELN来记录和管理更一般的临床观察结果，并管理与各种过程相关的文档。

These diverse information management needs require an ELN that is versatile and highly configurable to accommodate multiple and divergent workflows, yet robust and structured enough to maintain integrity and uniformity of processes.

The Arxspan Notebook has the flexibility to effectively manage recording of scientific and clinical information from its earliest stages at the bench all the way through to the clinical trials process.

科学家在ARXSPAN笔记本中具有完整的ELN功能，可记录发现研究和临床前的安全和代谢数据。可以部署自定义工作流程以管理样品，动物和材料工作流程。

Patient questionnaires and approvals, sample protocols, test results, and project plans can be attached to experiments or other workflows. Arxspan Notebook has the capacity to store large data files, such as next generation sequencing data. The Arxspan platform is 100% cloud-based, fostering information sharing throughout the clinical research ecosystem’s network of sites, pharmaceutical companies, and academic research institutions. Biorepositories can be established and groups of patient samples can be linked to experiments for research and testing purposes. Arxspan Notebook has decision support capability so that clinically relevant data can be sorted, speeding clinical decision making. The system is 21 CFR Part 11 qualified and offers full experimental audit trails, digital signing and witnessing capability, and optional support for SAFE BioPharma signatures.

The pace of academic research is accelerating, and the speed with which collaborations are struck between universities and governmental and non-governmental laboratories, as well as industry, continues to grow.

学术研究人员越来越多地分享他们的数据，目的是出版，临床试验启动以及为其工作获得资金。需要一个系统充分注册其科学实验数据，并有选择地并安全地共享它正在增长。此外，生物学研究中正在产生的信息量是巨大的，并且不断增长，从而增加了对管理这种科学信息的强大系统的需求。

Academic researchers have specialized requirements for an electronic laboratory notebook. They need a comprehensive resource that is able to store large amounts of data and attach files of any format. Their information needs to be organized and searchable by particular experiment or subject matter, not just chronologically. Their ELN needs to do be able to safely archive data for years to come and to have the capability to share data with anyone at any time

首席研究人员必须能够审查其实验室成员的实验进展，并能够轻松地生成用于沟通和出版的实验报告。学术研究人员通常还需要访问中央系统以存储试剂和冷冻内容，同时使笔记本保持私密和机密。最后，ELN需要直观，易于使用且具有成本效益。

The Arxspan Notebook system is entirely cloud-based, with no servers or databases to purchase and install. Users of the system can be added or subtracted with the click of a button at any time. Furthermore, scientists can be allowed access to any notebook on the system with the click of a button, allowing flexibility of the size and dynamic of research teams associated with any given project. Also, the cloud-based nature of the system allows for secure and efficient collaboration between academia, government, NGOs, and industry. The Arxspan Inventory module can create a central location to track materials throughout the institute, as well as materials produced within a core facility.

包括动物和细胞系管理在内的专门工作流程使得在体外以及体内阶段记录过程变得容易。

Multiple devices are supported by Arxspan Notebook, allowing for free movement between office and laboratory. Instrument files can be attached to experiments, and copying and pasting functions are easy to use. Arxspan has an intuitive, attractive, and easy to use interface. PIs can monitor the work product of their entire lab in real time and can quickly generate comprehensive PDF versions of an entire experiment for the purposes of sharing or using as a basis for drafting a research paper. Data is protected in Arxspan’s secure data center, and all information is stored in a centralized repository rather than on shared or personal drives.

Improve basic scientific research speed, effectiveness, and productivity in your organization.