Preclinical Micro-CT

SKYSCAN 1272

High-resolution 3D X-ray Microscopy
herostageskyscan1272

Destaques

Highlights

0.6 m²
脚印
A desktop system that fits in every lab
16-position
External sample changer
Unattended high-throughput analysis
200 Mp
每片像素
Enabling high resolution imaging

SKYSCAN 1272 – High-resolution XRM

The desktop SKYSCAN 1272 is an innovative high-resolution 3D X-ray microscope based on micro computed tomography (micro-CT) technology, which can non-destructively visualize with more than 200 Megapixel (14450 x 14450 pixels) in every virtual slice through an object.

将样品和大型CCD摄像头移动尽可能接近源的能力大大提高了测得的强度。这就是为什么Skyscan 1272与具有固定相机位置的传统系统相比,扫描速度高5倍。


1272年SKYSCAN提供了自动选择的标准ameters with Genius-Mode. Magnification, energy, filter, exposure time and background corrections can all be optimized automatically with a single click.
可选的16位样品更换器可用于无人看管的高吞吐量扫描。

SKYSCAN 1272 is complemented by 3D.SUITE. This comprehensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.

Características

Key Features

SKYSCAN 1272 Features

Genius Mode

1272年SKYSCAN提供了自动选择的标准ameters with Genius-Mode. Magnification, energy, filter, exposure time and background corrections can all be optimized automatically with a single click.


Furthermore, both the sample and large-format CCD camera can be positioned as close as possible to the source, which substantially increases the measured intensity. That is why SKYSCAN 1272 scans up to 5 times faster compared to conventional systems with fixed camera position.

SKYSCAN 1272 Features

Sample changer

SKYSCAN 1272 can optionally be equipped with an external 16-position sample changer to increase throughput for QC and routine analysis.

The sample changer accepts a variety of sample sizes, up to a diameter of 96 mm.

Samples can be can be easily replaced at any time without interrupting an ongoing scanning process. New samples are automatically detected, and LED‘s indicate the status for every scan: ready, scanning, done.

SKYSCAN 1272 Features

原位阶段

The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.

Bruker's heating and cooling stages can reach temperatures of up to +80ºC, or 30ºC below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.

Aplicações

突出显示应用程序

Bone Applications

Skyscan 1272成功了Skyscan 1072和Skyscan 1172型号,它们之间至少占了整个Microct骨形态计量学文献的至少一半。这是高分辨率高分和易用性的高分辨率的基准。这使其成为从骨质疏松和关节炎到骨肿瘤和骨髓瘤以及大规模基因表型的理想解决方案。

  • 最终表现在桌面模型中,体素size to 0.4um, x-ray voltage 20-100kV, provide resolution and contrast to analyze bone osteocyte lacunae and vessel canals.
  • High throughput and automated batch scanning including an optional sample changer for 16 preloaded samples, a powerful set-up for genetic screening of thousands of phenotypes, of mice or zebrafish for trabecular and cortical bone parameters.
  • Advanced 3D image analysis functions include phase contrast / retrieval (Paganin, small angle), 3D registration, allowing flexible solutions for all disease models and analysis requirements.
  • Bone morphometry (ASBMR nomenclature) with comprehensive 3D and 2D parameters, with densitometry including BMD calibration references over the preclinical size range.

Soft tissues

Ex vivo scanning of biological tissues is a very good way to show their internal structures non-destructively. A contrast agent or chemical drying can improve the image quality by further enhancing or differentiating densities. The SKYSCAN 1272 is the ideal platform for such imaging with its resolution, easy sample handling and high throughput – that’s why you will find so many publications using this scanner.

  • 该系统的典型应用是小鼠肺中肿瘤生长或血管化的可视化。肺气肿和纤维化也清晰可见。
  • 最终表现在桌面模型中,体素size to 0.4um, x-ray voltage 20-100kV, provide resolution and contrast down to the lung alveolar level.
  • Stabilizing these fragile or wet tissues during scanning can be challenging, a special set of Bruker developed specimen chambers can take care of this.
  • Full in-house software solution for lung tumor morphometric analysis, auto-separation of lung from other tissues in CT-Analyser software.

Plant and Animal Biology

MicroCT is exceptionally good for the visualization of internal structures in the finest details of the tissues of plants and animals. This imaging method differentiates between densities without harming or destroying the scanned object. That’s why zoology and botany are fast-growing microCT applications with SKYSCAN 1272 users at the forefront. A wide range of different living organisms can be visualized and analyzed with minimal or no sample-treatment.

  • High resolution scanning with object detection down to 0.4um combined with an 11 or 16 megapixel camera for high resolution in a useful volume.
  • Due to the continuous voltage range of the sources, and 6 internal energy filters, the perfect scan set up for each different sample can be guaranteed.
  • 全面的3D图像分析能力,包括形态计和光密度计,相位对比度 /检索(Paganin,小角度),3D注册,分割和高级图像处理方法。

Especificações

SKYSCAN 1272 Specifications

Feature

Specification

Benefit

X射线源

20 – 100 kV

10 W

< 5 µm spot size at 4 W

Maintenance-free sealed X-ray source

Fast scans for QC, or 4D XRM

X-ray detector

CCD detector

11 MP (4032 x 2688)

16 MP (4904 x 3280)

实现最高分辨率的精细探测器

对象大小

75 mm diameter

70 mm height

能够从中小型样本大小扫描

Sample changer

(optional)

16 samples up to 50 mm diameter

8 samples up to 96 mm diameter

外部访问

Unattended high throughput

Any combination of large and small samples

Add/remove samples at any time without interrupting the actual scan

Dimensions

W 1160 mm x D 520 mm x H 330 mm

重量150公斤

Space-saving desktop system that fits in every lab

Power supply

100-240V AC,50-60Hz,最大3A。

最低安装要求,标准电源就足够了

软件

位置,扫描,重建和分析

Bruker XRM解决方案包括收集和分析数据所需的所有软件。具有用户指导参数优化的直观图形用户界面支持专家和新手用户。通过使用最新的GPU动力算法,重建时间大大减少了。CTVOX,CTAN和CTVOL结合在一起,形成了一个强大的软件套件,用于模型的定性和定量分析。

Measurement Software:
SKYSCAN 1272 – Instrument control, measurement planning and collection

重建软件:
NRECON - 将2D投影图像转换为3D卷

分析软件:
DATAVIEWER– Slice-by-slice inspection of 3D volumes and 2D/3D image registration

CTVOX- 通过音量渲染的现实可视化

CTAN– 2D/3D image analysis & processing

CTVOL– Visualization of surface models to export for CAD or 3D printing

Notícias e Eventos

Apoio

SKYSCAN 1272 - Service & Support

Available services include

  • Help desk support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software problems
  • Web-based remote instrument service for service diagnosis and applications support
  • Merged reality support with Help Lightning – a virtual engineer at your side (video)
  • 根据您的要求,计划维护
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • Compliance services for installation qualification, operational qualification / performance verification
  • Site planning and relocation

Bruker Support

On our支持网站you will find:

软件Updates

  • System software updates are available online to registered users.

Documentation

  • Product manuals and installation guides are available online to registered users.

实验室

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory