Preclinical Micro-CT

SKYSCAN 1272 CMOS EDITION

High-resolution 3D X-ray Microscopy

Destaques

Highlights

0.6 m²
脚印
A desktop system that fits in every lab
16-position
External sample changer
Unattended high-throughput analysis
16 Mp
CMOS Camera
Enabling high resolution imaging
SKYSCAN 1272 CMOS life science brochure
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SKYSCAN 1272 CMOS EDITION – High-resolution microCT

The desktop SKYSCAN 1272 CMOS is an innovative high-resolution 3D X-ray microscope based on micro computed tomography (micro-CT) technology, and builds on the trusted SKYSCAN 1272 platform to integrate the latest X-ray technologies.


其最先进的16百万像素SCMOS X射线检测器提供具有优越分辨率的高对比度图像。扩展的检测器视野和对X射线的灵敏度增强的敏感性最长两倍。每切最高11200 x 11200像素的非凡本机分辨率允许放大3D体积的任何部分,而无需重新降低样品。新的清洁图像表扫描模式从一开始就大大减少了典型的CT伪像,因此提供了高质量的图像,而没有繁琐的后验校正。


This top performance is paired with low cost of ownership. Our desktop SKYSCAN 1272 CMOS Edition can be placed on any laboratory desk and consequently does not occupy a lot of expensive lab space. A standard domestic power plug is all you need to start running the instrument, no water chiller or additional compressor. There are also no further hidden costs as the industry-grade sealed X-ray source is maintenance-free. SKYSCAN 1272 is complemented by 3D.SUITE. This comprehensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.

Características

关键Features

SKYSCAN 1272 CMOS Features

Genius Mode

The SKYSCAN 1272 offers automatic selection of parameters with Genius-Mode. Magnification, energy, filter, exposure time and background corrections can all be optimized automatically with a single click.


Furthermore, both the sample and large-format sCMOS camera can be positioned as close as possible to the source, which substantially increases the measured intensity. That is why SKYSCAN 1272 scans up to 5 times faster compared to conventional systems with fixed camera position.

SKYSCAN 1272 CMOS Features

Sample changer

SKYSCAN 1272 can optionally be equipped with an external 16-position sample changer to increase throughput for QC and routine analysis.

The sample changer accepts a variety of sample sizes, up to a diameter of 25 mm.

Samples can be can be easily replaced at any time without interrupting an ongoing scanning process. New samples are automatically detected, and LED‘s indicate the status for every scan: ready, scanning, done.

SKYSCAN 1272 CMOS Features

原位阶段

The Bruker material testing stages are designed to perform compression experiments up to 4400 N and tensile experiments up to 440 N. All stages automatically communicate through the system’s rotation stage, without the need of any cable connections. Using the supplied software, scheduled scanning experiments can be set up.

Bruker's heating and cooling stages can reach temperatures of up to +80ºC, or 30ºC below ambient temperature. Just like the other stages, no extra connections are needed, and there is an automatic recognition of the stage. Using the heating & cooling stages, samples can be examined under non-ambient conditions, to evaluate the effect of temperature on the sample’s microstructure.

Aplicações

突出显示应用程序

Bone Applications

Skyscan 1272成功了Skyscan 1072和Skyscan 1172型号,它们之间至少占了整个Microct骨形态计量学文献的至少一半。这是高分辨率高分和易用性的高分辨率的基准。这使其成为从骨质疏松和关节炎到骨肿瘤和骨髓瘤以及大规模基因表型的理想解决方案。

  • Ultimate performance in a desktop model, voxel size to 0.45um, x-ray voltage 40-100kV, provide resolution and contrast to analyze bone osteocyte lacunae and vessel canals.
  • High throughput and automated batch scanning including an optional sample changer for 16 preloaded samples, a powerful set-up for genetic screening of thousands of phenotypes, of mice or zebrafish for trabecular and cortical bone parameters.
  • Advanced 3D image analysis functions include phase contrast / retrieval (Paganin, small angle), 3D registration, allowing flexible solutions for all disease models and analysis requirements.
  • 骨形态测量学与compreh (ASBMR命名)ensive 3D and 2D parameters, with densitometry including BMD calibration references over the preclinical size range.

Soft tissues

Ex vivo scanning of biological tissues is a very good way to show their internal structures non-destructively. A contrast agent or chemical drying can improve the image quality by further enhancing or differentiating densities. The SKYSCAN 1272 is the ideal platform for such imaging with its resolution, easy sample handling and high throughput – that’s why you will find so many publications using this scanner.

  • 该系统的典型应用是小鼠肺中肿瘤生长或血管化的可视化。肺气肿和纤维化也清晰可见。
  • 台式机型号的最终性能,体素尺寸为0.45UM,X射线电压40-100kV,可分辨率和对比度降至肺肺泡水平。
  • Stabilizing these fragile or wet tissues during scanning can be challenging, a special set of Bruker developed specimen chambers can take care of this.
  • Full in-house software solution for lung tumor morphometric analysis, auto-separation of lung from other tissues in CT-Analyser software.

Plant and Animal Biology

MicroCT is exceptionally good for the visualization of internal structures in the finest details of the tissues of plants and animals. This imaging method differentiates between densities without harming or destroying the scanned object. That’s why zoology and botany are fast-growing microCT applications with SKYSCAN 1272 users at the forefront. A wide range of different living organisms can be visualized and analyzed with minimal or no sample-treatment.

  • High resolution scanning with object detection down to 0.45um combined with a 16 megapixel sCMOS camera for high resolution in a useful volume.
  • Due to the continuous voltage range of the sources, and 6 internal energy filters, the perfect scan set up for each different sample can be guaranteed.
  • 全面的3D图像分析能力,包括形态计和光密度计,相位对比度 /检索(Paganin,小角度),3D注册,分割和高级图像处理方法。

Especificações

SKYSCAN 1272 CMOS Specifications

功能

Specification

Benefit

X射线源

40 – 100 kV

10 W

< 5µm光斑大小4 W

Maintenance-free sealed X-ray source

Fast scans for QC, or 4D XRM

X-ray detector

16 MP sCMOS detector (4096 x 4096 pixels)

实现最高分辨率的精细探测器

对象大小

75 mm diameter

80 mm height

能够从中小型样本大小扫描

Sample changer

(optional)

16 samples up to 25 mm diameter

外部访问

Unattended high throughput

Any combination of large and small samples

Add/remove samples at any time without interrupting the actual scan

Dimensions

W 1160 mm x D 520 mm x H 330 mm

重量150公斤

Space-saving desktop system that fits in every lab

Power supply

100-240V AC,50-60Hz,最大3A。

最低安装要求,标准电源就足够了

软件

位置,扫描,重建和分析

Bruker XRM解决方案包括收集和分析数据所需的所有软件。具有用户指导参数优化的直观图形用户界面支持专家和新手用户。通过使用最新的GPU动力算法,重建时间大大减少了。CTVOX,CTAN和CTVOL结合在一起,形成了一个强大的软件套件,用于模型的定性和定量分析。

Measurement Software:
Skyscan 1272 CMOS版 - 仪器控制,测量计划和收集

重建软件:
NRECON - 将2D投影图像转换为3D卷

分析软件:
DATAVIEWER– Slice-by-slice inspection of 3D volumes and 2D/3D image registration

CTVOX- 通过音量渲染的现实可视化

CTAN– 2D/3D image analysis & processing

CTVOL– Visualization of surface models to export for CAD or 3D printing

Notícias e Eventos

Apoio

SKYSCAN 1272 - Service & Support

Available services include

  • Help desk support from highly-skilled troubleshooting professionals, to isolate and resolve hard- and software problems
  • Web-based remote instrument service for service diagnosis and applications support
  • Merged reality support with Help Lightning – a virtual engineer at your side (video)
  • 根据您的要求,计划维护
  • Customer on-site repair and maintenance service
  • Spare parts availability typically over night or within a few working days worldwide
  • Compliance services for installation qualification, operational qualification / performance verification
  • Site planning and relocation

Bruker Support

On our支持网站you will find:

软件Updates

  • System software updates are available online to registered users.

Documentation

  • Product manuals and installation guides are available online to registered users.

实验室

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory