布鲁克的下一代
Skyscan 1278
Skyscan 1278是用于扫描小型实验室动物(小鼠,老鼠,...)的高吞吐量,独立的台式机体内桌面。
The large image field of view (up to 80 mm wide and 200 mm long) allows full body mouse scanning with a single camera field of view. Variable X-Ray energy combined with a range of filters ensures optimal image quality for diverse research applications including pneumology, cardiology and body composition analysis. The system can perform scanning with continuous gantry rotation and in step-and-shoot mode with scanning cycles down to 7.2 sec.
此外,Skyscan 1278体内微CT给动物施用低辐射剂量,允许在纵向临床前研究中进行多次扫描,而没有不必要的辐射诱发副作用的风险。完全集成的生理监测软件包允许始终通过视频流,ECG,温度和呼吸检测来监视和控制动物的健康。
Skyscan 1276由3D.Suite补充。这个广泛的软件套件涵盖了GPU加速重建,2D/ 3D形态学分析以及表面和体积渲染可视化。
Skyscan 1278提供了可兑换动物盒,可用于所有Bruker体内成像仪器中,用于从同一动物中共同注册功能和形态信息。盒式盒配有面膜和试管,用于麻醉气体,以及用于ECG电极和温度传感器的连接器。所有管子和触点都合并到单个连接器上,该连接器可以通过简单的小滑块连接到动物运输系统或从动物运输系统中分离。为了防止麻醉气体的泄漏,如果动物盒与动物运输系统断开连接,相应的连接阀可保持关闭。
The user interface of the SkyScan1278 system is simple and intuitive. The instrument can be controlled from the computer screen and also from the embedded force-sensitive touchscreen, which can be operated by gloved hands. The touchscreen allows selection of scanning protocol, adjusting animal bed position and control of imaging and scanning. Where multiple animal scans are started from the touchscreen, the software will automatically save acquired data to separate subfolders with incrementally assigned folder names and dataset file prefixes.
The SkyScan1278 control software includes a real-time on-screen dose meter. It indicates an estimation of the dose absorbed by the animal body during scanning. The measurement is based on the absorption calculated from X-ray projection images of the animal cross-calibrated with electronic dosimeter measurements. The dose meter shows accumulated dose or dose rate. It is calibrated for X-ray absorption in the standard mouse and rat cassettes. In this way it measures the X-ray dose absorbed in animal body itself during scanning. The dose absorbed by the animal during a scan is documented in the scan log-file together with all scan and reconstruction settings.
生理监测系统包括对动物进行实时运动检测,心电图和呼吸检测以及温度稳定的视频监测。一个5百万像素的颜色摄像头安装在动物床上方以及白色LED照明上,以在扫描过程中引入动物的实时图像。该软件从图像的用户选择区域分析了视频流,其中可见呼吸运动。这些运动被转换为运动波形,为时间分辨的重建提供呼吸时间标记。动物床上的面膜连接到空气/气流传感器以直接呼吸检测。动物盒中的ECG电极连接到敏感的ECG放大器。呼吸和心电图信号都在屏幕上数字化并显示为实时轮廓。监测还包括加热气流的温度稳定,该气流将扫描动物保持在选定的温度下,以防止在麻醉下冷却动物。
Calculating and visualizing body composition of the mouse or rat is easily accomplished in just a few steps. No additional contrast agent is needed to analyze body fat as it is one of the naturally occurring x-ray densities in the body, the others being lean tissue, lung tissue and bone. With the SKYSCAN 1278 body tissue composition analysis can be highly automated and high-throughput, suitable for genetic screening.
1278年SKYSCAN versatile lung imaging solution for both mouse and rat. Rat lungs are imaged in a single scan FOV thanks to the large and fast cMOS flat panel x-ray camera. The scanner and accompanying software provide sharply time-gated lung images in short scan times with safe levels of ionizing radiation. As with all SKYSCAN in vivo scanners, physiological monitoring is integrated at the heart of the instrument, with the welfare of the scanned animal the top priority.
Skyscan 1278是用于小鼠和大鼠的多功能心脏成像解决方案。借助大型且快速的CMOS平板X射线相机,将老鼠的心脏和肺部成像。扫描仪和随附的软件在短扫描时间内提供了急剧时期的心脏,肺和双(心脏肺门控)图像,并具有安全的电离辐射水平。与所有体内扫描仪一样,生理监测是仪器的核心,动物的福利是最重要的。
小鼠体内脂肪分布(橙色)的体积渲染,以50μm的体素尺寸扫描。
小鼠体的最大强度投影,在体内扫描。
小鼠骨骼的3D模型,对骨矿物质密度(BMD)进行了颜色编码。
横截面切成小鼠体,在50 µm体素大小的情况下扫描没有对比剂。
小鼠身体的3D动画,在50 µm体素大小的对比剂注射后进行扫描。
体积渲染了大鼠的3D图像,实际上打开以暴露脊柱。
横截面图像表示小鼠心跳的时间顺序,扫描体内after contrast agent injection.
Feature | 规格 | 益处 |
X射线源 | 20 - 65 KV,50W 自动化的4位滤波器更换器 |
Maintenance-free sealed X-ray source |
X射线检测器 | 主动像素CMOS平板板 3 MP (1944 x 1536) 75 µm像素大小 |
优秀的信噪比 大型视野 |
空间分辨率 | 50µm最小的像素尺寸 | Good resolution for in vivo imaging |
对象大小 | 直径80毫米 200 mm height |
能够扫描大量样本量 |
方面 | W 850毫米X D 1240毫米(带敞开的门1620毫米)X H 960毫米 重量240公斤 |
节省空间桌面系统,适合每个实验室 |
电源 | 100-240V AC,50-60Hz,最大3A。 | 最低安装要求,标准电源就足够了 |
Bruker XRM解决方案包括收集和分析数据所需的所有软件。具有用户指导参数优化的直观图形用户界面支持专家和新手用户。通过使用最新的GPU动力算法,重建时间大大减少。CTVOX,CTAN和CTVOL结合在一起,形成了一个强大的软件套件,用于模型的定性和定量分析。
测量软件:
Skyscan 1272 - 仪器控制,测量计划和收集
重建软件:
NRECON - 将2D投影图像转换为3D卷
分析软件:
DATAVIEWER- 逐片检查3D卷和2D/3D图像注册
CTVOX- 通过音量渲染的现实可视化
CTAN- 2D/3D图像分析与处理
ctvol- 可视化表面模型以导出CAD或3D打印
在我们的支持网站你会找到:
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