SkyScan 1278

Skyscan 1278是用于扫描小型实验室动物（小鼠，老鼠，...）的高吞吐量，独立的台式机体内桌面。

The large image field of view (up to 80 mm wide and 200 mm long) allows full body mouse scanning with a single camera field of view. Variable X-Ray energy combined with a range of filters ensures optimal image quality for diverse research applications including pneumology, cardiology and body composition analysis. The system can perform scanning with continuous gantry rotation and in step-and-shoot mode with scanning cycles down to 7.2 sec.

此外，Skyscan 1278体内微CT给动物施用低辐射剂量，允许在纵向临床前研究中进行多次扫描，而没有不必要的辐射诱发副作用的风险。完全集成的生理监测软件包允许始终通过视频流，ECG，温度和呼吸检测来监视和控制动物的健康。

The SKYSCAN 1276 is complemented by 3D.SUITE. This extensive software suite covers GPU-accelerated reconstruction, 2D/ 3D morphological analysis, as well as surface and volume rendering visualization.

The user interface of the SkyScan1278 system is simple and intuitive. The instrument can be controlled from the computer screen and also from the embedded force-sensitive touchscreen, which can be operated by gloved hands. The touchscreen allows selection of scanning protocol, adjusting animal bed position and control of imaging and scanning. Where multiple animal scans are started from the touchscreen, the software will automatically save acquired data to separate subfolders with incrementally assigned folder names and dataset file prefixes.

The physiological monitoring system includes video monitoring of an animal with real-time movement detection, ECG and breathing detection, and temperature stabilization. A 5 megapixel color camera is mounted above the animal bed along with white LED illumination to introduce a real-time image of the animal during the scan. The software analyses the video stream from a user-selected area of the image where breathing movement is visible. These movements are converted into a movement waveform to provide breathing time marks for time-resolved reconstructions. The face mask on the animal bed is connected to an air/gas flow sensor for direct breathing detection. The ECG electrodes in the animal cassette are connected to a sensitive ECG amplifier. Both breathing and ECG signals are digitized and displayed as real-time profiles on-screen. The monitoring also includes temperature stabilization by heated airflow, which maintains the scanned animal at a selected temperature, to prevent cooling of the animal under anaesthesia.

Calculating and visualizing body composition of the mouse or rat is easily accomplished in just a few steps. No additional contrast agent is needed to analyze body fat as it is one of the naturally occurring x-ray densities in the body, the others being lean tissue, lung tissue and bone. With the SKYSCAN 1278 body tissue composition analysis can be highly automated and high-throughput, suitable for genetic screening.

• 最快的扫描仅为7.2秒，并且简化的操作使小鼠或大鼠的高吞吐量易于获得。优化的过滤器和电压确保可能的辐射剂量最小。
• Physiological monitoring is design-central in SKYSCAN体内scanners, not an add-on. High quality video, breathing monitoring by video-movement and pressure, ECG and thermostat-controlled warming, with a port for external physiological instrumentation.
• 与单个锁定按钮相连的高级动物盒以进行完整的生理监测和麻醉措施，但可拆卸 - 通用布鲁克体内床。
• Full in-house software solution for tissue segmentation and 3D analysis, 3D registration of sequential scans to map progression with growth and time.

1278年SKYSCAN versatile cardiac imaging solution for both mouse and rat. The rat heart and lungs are imaged in a single scan FOV thanks to the large and fast cMOS flat panel x-ray camera. The scanner and accompanying software provide sharply time-gated cardiac, lung and dual (cardiac-lung gated) images in short scan times with safe levels of ionizing radiation. As with all SKYSCAN in vivo scanners, physiological monitoring is at the heart of the instrument, with the welfare of the animal the top priority.

• 高质量的视频，通过视频移动和压力进行呼吸监测，ECG和恒温器控制的变暖。外部进入扫描室的管道，包括毛细管（连续注射）。
• 与单个锁定按钮相连的高级动物盒以进行完整的生理监测和麻醉措施，但可拆卸 - 通用布鲁克体内床。A large carbon fiber bed for rats. Support for third party devices such as ventilators (e.g. Scireq FlexiventTM).
• Comprehensive time-gating solutions: prospective and retrospective, time and image based intrinsic gating. Continuous rotation available for fast low-dose gated scanning.
• 4D的心脏功能分析的完整内部软件解决方案：射血量，其他心脏腔和主动脉，心脏波训练的时间分析，包括规律性和分形，以及CT-Analyserser软件中心脏周期的灵活分割和分析。

Bruker XRM解决方案包括收集和分析数据所需的所有软件。具有用户指导参数优化的直观图形用户界面支持专家和新手用户。通过使用最新的GPU动力算法，重建时间大大减少。CTVOX，CTAN和CTVOL结合在一起，形成了一个强大的软件套件，用于模型的定性和定量分析。

Measurement Software:
SKYSCAN 1272 – Instrument control, measurement planning and collection

重建软件：
NRECON - 将2D投影图像转换为3D卷

分析软件：
DATAVIEWER– Slice-by-slice inspection of 3D volumes and 2D/3D image registration

CTVOX- 通过音量渲染的现实可视化

CTAN– 2D/3D image analysis & processing

CTVOL- 可视化表面模型以导出CAD或3D打印