Adding the 4th dimension
Increases depth of LC-MS/MS workflows
离子迁移率是对质谱的强大扩展,可提供有关离子三维结构的信息,并增加了对复合表征的峰值容量和置信度。
timsTOF was engineered by Bruker experts as an open platform to accelerate the adoption of ion mobility-mass spectrometry analysis across research applications.
高度独特的TIMS设计实现了无与伦比的占空比(高达100%),IMS分辨率(R> 200)的显着改善,前所未有的碰撞横截面(CCS)可重复性和高灵敏度。
With the flip of a switch, augment the peak capacity of your analytical system beyond chromatography and time-of-flight separation. No penalty in analysis time, no penalty in sensitivity.
timsTOF features adjustable ion mobility separation based on Trapped Ion Mobility Spectrometry (TIMS), so you can explore samples in various and meaningful ways. Furthermore, timsTOF uses an open data format (*.tdf) that introduces full transparency, efficiency and flexibility into your data analysis strategy.
timsTOF combines high ion mobility resolution with ultra-high resolution QTOF technology for optimal performance. imeXTM technology further boosts the functionality by making ion mobility resolution an adjustable parameter.
Investigate your sample in imeX survey mode for mobility-resolved full scans, and then extend your workflow with a detailed examination of selected compounds and precise collisional cross sections (CCS). Increase ion mobility resolution up to 200 for unique insights into your samples in imeX ultra mode.
自信是基于识别化合物orthogonal qualifiers that are reliably reported with high accuracy. With timsTOF, exact mass measurements (low ppm) are complemented with Bruker’s unique isotopic pattern fidelity (True Isotopic Pattern or TIPTM) and precise collisional cross section determination (<0.5% RSD).
Instrument geometry and the positioning of ion mobility separation prior to quadrupole isolation and fragmentation generate clear fragmentation spectra to further enhance certainty of identifications.
Analyze isomeric compounds
Ion mobility separation is a very powerful approach to separate isobaric or isomeric compounds. Especially in combination with high resolution accurate mass spectrometry, ion mobility separation greatly enhances substance identification and characterization capabilities, and provides an additional physical property of compounds, the CCS values.
高信心法医筛查
离子迁移率结合高分辨率(HRES)质谱法可以识别和表征已知的以及未知的设计师药物分析物及其代谢物。
表征植物代谢产物和次生代谢产物
“我们已经在实验室中使用了离子移动性,但是Timstof现在提供的离子移动性分辨率更高,基于这项技术的不同应用程序有很大的空间。”
For Research Use Only. Not for use in clinical diagnostic procedures.