MS软件

SCiLS™ Lab

世界领先的软件,用于分析来自所有主要质谱供应商的质谱成像数据,包括Bruker的Flex系列和MRMS

Turn data into knowledge

一个软件中的分析和可视化

scils.

Punti salienti

MS软件

SCiLS™ Lab

使用方便
支持来自其他主要质谱供应商的所有主要Bruker仪器和数据。
Visualization
2D and 3D visualization allows a multitude of applications in pharmaceutical, medical, and industrial research.
Analysis
下一代机床学习算法的先进处理和分析。
Integrated
MALDI分子药物成像仪,Rapiflex Maldi Tissuetyper的组成部分,以及来自Timstof Flex的Spatialomx工作流程。

CarateriStiche.

SCiLS Lab

Software for MS imaging data analysis

来自Bruker的软件从未如此容易的MALDI成像数据的统计分析。

基本可视化和处理

  • Instant visualization of ion images and spectra
  • 众多可视化选项
  • 易于使用的计算工具

高级处理和分析
  • Advanced machine learning algorithms for data sets of virtually unlimited size
  • Comparative analysis for uncovering discriminative m/z-markers
  • Co-localization analysis for discovering correlated m/z-values
  • Spatial segmentation for automatic annotation of prominent features
  • Component analysis for extraction of underlying trends
  • Multiple annotations for characterizing regions in clinical and pre-clinical studies
  • 未标记样本分类的分类模型
  • Perform absolute quantitation for MS imaging data
  • 支持基于组织的Spatialomx工作流程并可视化组织中检测到的化合物的分布

Also available
  • Construction, visualization, and analysis of three-dimensional models
SCILS™实验室是行业的选择工具,用于从质谱中获得新的洞察力。软件在科学和工业中使用,软件在分析和可视化方面设定了新的标准,简化了日常工作和提高研究输出。


系统要求
The following system requirements apply:

  • 英特尔酷睿i7处理器或英特尔Xeon处理器(等价或更好)
  • Microsoft Windows 7 64 Bit or Microsoft Windows 10 64 Bit operating system
  • 32 GB的RAM
  • SATA III solid-state drive (SSD)
  • Full-HD display (1920 x 1080)
  • 显卡支持OpenGL 3.2
The SSD should be used to host the SCiLS™ Lab files. The best way to improve the recommended system is to add more RAM and a RAID0 configuration of SATA III SSDs. The data which shall be imported or processed should then be stored on the SSDs.

优惠

SCiLS Lab

World-leading software for analysis of mass spectrometry imaging

SCILS™实验室将数据集成了所有主要质谱供应商,包括Bruker的数据Flex系列MRMS, as well as datasets provided in the open imzML format.

Comparative analysis of multiple samples can be visualized in both 2D and 3D, enabling a multitude of applications in制药aceutical drug development,组织分离生物标志物研究, and translational pathology research to complement immunohistochemistry.

SCILS™实验室的MSI定量工作流程可以轻松地直接从组织定量靶分子。Scils™实验室与Spatialomx工作流程集成MetaboScape®和visualizes the annotated MALDI molecular tissue images of detected features (metabolites, lipids, glycans).

为了timsTOF fleXion mobility data, SCiLS™ Lab can display the mobility images allowing CCS-aware data interpretation.

申请

SCiLS Lab

Label-free molecular imaging mass spectrometry ranging from proteins to small molecules


SCILS™实验室可用于分析一个或多个谱技术成像数据集. Multiple data sets can be loaded and spatially aligned in a tiled manner. Compositions of data sets of virtually unlimited size can be visualized and statistically analysed for detailed interpretation. Also, SCiLS™ Lab can be used for construction of 3D MALDI Imaging data from consecutive 2D datasets, and visualization and analysis of 3D MALDI Imaging data.

Distribution of three distinct m/z values in a 3D reconstruction of 49 sagittal mouse brain sections containing a non-metastasizing cerebellar tumor with SCiLS™ Lab.
Statistical analysis with SCiLS™ Lab: Automatically group samples according to meta-data provided with experiments – perform classification and prediction with machine learning methods for tissue typing or biomarker discovery.


来自临床病理学的大队列样品
In pioneering biomarker studies, thediscovery of discriminating ions由手动完成或使用自定义写软件脚本进行。因为样品的数量 - 因此,在生物标志物研究中分析的数据量是巨大的,手动数据分析既耗时又出错。

现在可以在SCILS™实验室中轻松进行识别病理生理改变的光谱特征的自动阐明。只需单击一下,SCILS™实验室会自动量化所有离子区分不同的生物状态。可以很容易地导出所得到的新型生物标志物候选人以进行后续分析。

发现使用Scils™Lab的单击距离酒店的强大数据挖掘功能。

Whole body imaging
对于2006年开展的开创性工作,全身MALDI成像挑战方法以及计算方面。想象药物和代谢物分布在全身组织部分内,使用各种商业,学术和定制软件进行几个手动数据处理步骤。

现在可以使用一个软件执行由数百万光谱组成的数据集的所有处理。从多个单独的数据集注册到一个分析文件到预处理谱到全面的统计分析,Scils™Lab提供整个数据分析工作流程。

Label-free targeted imaging and distribution mapping for drug discovery and DMPK/PD: Low operational cost and high specificity – differentiate drug and metabolite distributions, quantify target compounds, and integrate with histology.

Webinar

Testimonianze.

"With SCiLS Lab our team saved endless hours of manual comparisons. This unique feature was eagerly anticipated by us."

Rita Casadonte, PhD, Proteopath GmbH