Skyscan 1276 CMOS版本

Skyscan 1276 CMOS版是高性能，独立的，快速的，台式机，体内微型ct，用于扫描小型实验室动物（小鼠，老鼠，...）和生物样品的不断变化放大倍率。有可选的大型动物运输系统（LATS），使该系统还可以安装包括兔子在内的大型动物。

的SKYSCAN 1276 CMOS Edition has an unrivalled combination of high resolution, big image size, round and spiral (helical) scanning and reconstruction, and low dose imaging. The image field of view up to 75 mm wide and 310 mm long allows full body mouse and rat scanning. The variable magnification allows scanning bone and tissue samples with high spatial resolution down to 2.8 µm pixel size. Variable X-Ray energy combined with a range of filters ensures optimal image quality for diverse research applications from lung tissue to bone with metal implants. The system can perform scanning with continuous gantry rotation and in step-and-shoot mode with scanning cycles down to 3.9 sec. Furthermore, the SKYSCAN 1276 CMOS in vivo microCT administers a low radiation dose to the animals allowing multiple scans in longitudinal preclinical studies without the risk of unwanted radiation-induced side effects. The fully integrated physiological monitoring package allows monitoring and controlling the animal's wellbeing at all times through a video stream, ECG, temperature and breathing detection.

Skyscan 1276 CMOS由3D.Suite补充。这个广泛的软件套件涵盖了GPU加速重建，2D/ 3D形态学分析以及表面和体积渲染可视化。

Skyscan 1276 CMOS系统提供可交换的动物盒，可用于所有Bruker内部体内成像仪器，例如MRI，MIRI-PET，MICRO-SPECT，MICRO-SPECT，BIO-LOUMENECTIC，BIO荧光，生物荧光等，以收集多模式信息。它允许从同一动物共同注册功能和形态信息。

The user interface of the SKYSCAN 1276 CMOS system is simple and intuitive. The instrument can be controlled from the computer screen and also from the embedded force-sensitive touchscreen, which can be operated by gloved hands. The touchscreen allows selection of scanning protocol, adjusting the animal bed position and control of imaging and scanning. Where multiple scans are started from the touchscreen, the software will automatically save acquired data to separate subfolders with incrementally assigned folder names and dataset file prefixes.

The SkyScan1276 control software includes a real-time on-screen dose meter. It indicates an estimation of the dose absorbed by the animal body during scanning. The measurement is based on the absorption calculated from X-ray projection images of the animal cross-calibrated with electronic dosimeter measurements. The dose meter shows accumulated dose or dose rate. It is calibrated for X-ray absorption in the standard mouse and rat cassettes. In this way it measures the X-ray dose absorbed in animal body itself during scanning. The dose absorbed by the animal during a scan is documented in the scan log-file together with all scan and reconstruction settings.

生理监测系统包括对动物进行实时运动检测，心电图和呼吸检测以及温度稳定的视频监测。一个5百万像素的颜色摄像头安装在动物床上方以及白色LED照明上，以在扫描过程中引入动物的实时图像。该软件从图像的用户选择区域分析了视频流，其中可见呼吸运动。这些运动被转换为运动波形，为时间分辨的重建提供呼吸时间标记。动物床上的面膜连接到空气/气流传感器以直接呼吸检测。动物盒中的ECG电极连接到敏感的ECG放大器。呼吸和心电图信号都在屏幕上进行数字化并显示为实时轮廓。监测还包括加热气流的温度稳定，该气流将扫描动物保持在选定的温度下，以防止在麻醉下冷却动物。