NMR Clinical Research Solutions

Avance IVDR

通过按钮,标准化和完全自动化的核磁共振(NMR)溶液来推进人类生物流体的代谢组学研究

Furthering human disease research

使用强大的技术

avance-ivdr

Основныемоменты

Standardized
Standard Operating Procedures (SOP’s) for preparation and measurement of human biofluid samples ensuring the highest spectral quality and reproducibility for the generation of identical spectra, independent of the lab, user, and system.
Enabling Collaboration
Because of the strict standardization of the Bruker Avance IVDr platform, all date and results can be shared among research groups worldwide and can be used for common data analysis.
Single Analysis
在一次采集中,在混合物中自动迅速量化了数百种代谢产物,而无需分离,将生物流体变成数据。

标准化的核磁共振(NMR)光谱平台可实现成本效益,高性能NMR临床前筛选和IVD-by-NMR发现和验证(在RUO级别)的新型NMR分析。新的Avance IVDR系统目前仅用于研究使用,是NMR临床前研究和筛查以及IVD-by-NMR研究的完整,经过验证和标准化的平台。

It features high sensitivity and information-rich output at 600 MHz proton-NMR frequency, and incorporates advanced hardware, software, automation, spectral libraries and standard operating procedures (SOPs) for high-performance biofluid assay validation and pre-clinical screening. Customer benefits include higher information content and spectral feature differentiation compared to low-field NMR systems, as well as excellent reproducibility, high throughput and potentially dramatically lower cost per sample for better preparation and support of clinical screening and IVD-by-NMR discovery and validation (on RUO level).

Особенности

特征

  • 最小的样本preparationn
  • Non-destructive measurement
  • 在高吞吐量筛选模式下完全自动化
  • Highest reproducibility and data quality from sample to sample and instrument to instrument
  • Quantification of large sets of metabolites with automated reporting
    Classification and discriminiation using statistical tools with automated reporting
  • Low cost per sample and lowest cost per parameter, with small footprint to suit every lab

Преимущества

Benefits

  • 无需复杂的样品准备或样品识别
  • 易用性 - 不需要NMR的操作员专业知识
  • Highest reproducibility and data quality under full automation – anytime & anywhere
  • Handling of large data sets with simple retrieval of information
  • Rapid transfer from spectra to relevant information
  • 回顾性分析
  • Integration of spectra and results from different groups world wide

Спецификации

Specifications

High Performance and Throughput IVD-by-NMR Research

Paving the way for worldwide epidemiological studies as well as for preclinical research.

Avance IVDR专用于基于NMR的临床前体外筛查和研究,以易用和最高的数据质量,可靠性和可重复性优化,如右侧图所示。新的标准化平台提供条形码分析,通过LIMS系统控制,高通量AutoSampler SampleJet™,远程访问以及自动分析以及可自定义的分析结果报告。

Based on Bruker-validated SOPs, the AVANCE IVDr platform enables the development of future potential diagnostic tools for body-fluids that can address a variety of medical questions. The SOPs guarantee the preparation of highly reproducible clinical data, enabling the exchange and validation of novel NMR assays between laboratories on a global basis. In a translational clinical research environment the results produced by these NMR assays can easily be transferred into potential clinical screening and future IVD use.

This level of large-scale health-related NMR screening is paving the way for worldwide epidemiological studies as well as for pre-clinical in vitro research. The benefits have been significant: facilitated by the low cost per sample and the even lower cost per parameter as compared to established single parameter screening methods.

确定疾病原因,提供个性化患者治疗的新型NMR方法现在使许多临床研究人员能够制定预防策略。

Вебинары

→зы

Testimonials

采访现象中心的安东尼·多纳(Anthony Dona)
Interview Prof. Jeremy Nicholson

Поддержка

Labscape

Service & Life Cycle Support for Magnetic Resonance and Preclinical Imaging

Bruker’s commitment to provide customers with unparalleled help throughout the buying cycle, from initial inquiry to evaluation, installation, and the lifetime of the instrument is now characterized by the LabScape service concept.

LabScape Maintenance Agreements, On-Site On-Demand and Enhance Your Lab are designed to offer a new approach to maintenance and service for the modern laboratory